Dengue encephalitis-associated immunopathology in the mouse model: Implications for vaccine developers and antigens inducer of cellular immune response
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- 作者：Ernesto Marcosa ; 1 ; Laura Lazoa ; 1 ; Lá ; zaro Gila ; lazaro.gil@cigb.edu.cu" class="auth_mail" title="E-mail the corresponding author ; Alienys Izquierdob ; Edith Suzartea ; Iris Valdé ; sa ; Aracelys Blancoa ; Julio Ancizara ; José ; Suá ; rez Albaa ; Yusleydis de la C. Pé ; reza ; Karen Cobasa ; Yaremis Romeroa ; Gerardo Guillé ; na ; Marí ; a G. Guzmá ; nb ; Lisset Hermidaa ; lisset.hermida@cigb.edu.cu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dengue ; Vaccine ; Encephalitis ; Animal model ; Mouse
- 刊名：Immunology Letters
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：176
- 期：Complete
- 页码：51-56
- 全文大小：1218 K
文摘
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Cell-mediated immunity has a protective role in mouse model of Dengue encephalitis.
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There is immunopathology associated to the mouse model of Dengue encephalitis.
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Dengue intracranial challenge induces immune cell recruitment within the brain.