Touch Receptors Undergo Rapid Remodeling in Healthy Skin
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- 作者：Kara L. Marshall1 ; 2 ; 7 ; Rachel C. Clary1 ; 3 ; 7 ; Yoshichika Baba1 ; Rachel L. Orlowsky4 ; 5 ; Gregory J. Gerling4 ; 5 ; Ellen A. Lumpkin1 ; 2 ; 3 ; 6 ; 8 ; eal2166@columbia.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：tactile ; somatosensory ; neuronal plasticity ; Merkel cell ; anagen ; hair cycle ; touch ; skin
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：8 November 2016
- 年：2016
- 卷：17
- 期：7
- 页码：1719-1727
- 全文大小：3618 K
文摘
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Tactile sensory afferents are highly plastic during hair growth in mice
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Merkel cells are reduced and neuronal arbors are simplified in anagen touch domes
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Tactile behavior and electrophysiology show decreased reliability during hair growth
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Simulations reveal simple rules that explain Merkel cell-neurite complex remodeling