Quality of Life of Adolescent Kidney Transplant Recipients

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• 作者：Allison Tong ; PhD^a ; ^b ; ^{AllisonT@health.usyd.edu.au} ; Lidwien Tjaden ; DRS^a ; Kirsten Howard ; PhD^b ; Germaine Wong ; PhD^b ; Rachael Morton ; MScMed^b ; Jonathan C. Craig ; PhD^a ; ^b
• 关键词：HRQOL ; Health-related quality of life ; HUI ; Health Utilities Index ; HUI2 ; Health Utilities Index Mark 2 ; HUI2/3 ; Health Utilities Index Mark 2/3 ; HUI3 ; Health Utilities Index Mark 3 ; QOL ; Quality of life ; VAS ; Visual analog scale
• 刊名：The Journal of Pediatrics
• 出版年：2011
• 出版时间：October, 2011
• 年：2011
• 卷：159
• 期：4
• 页码：670-675.e2
• 全文大小：160 K

文摘

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Objective

To elicit utility-based quality of life (QOL) of adolescent kidney transplant recipients.

Study design

We measured QOL in adolescent transplant recipients by using a visual analog scale (VAS), and 2 utility-based QOL measures, the Health Utilities Index (HUI) Mark 2/3 (HUI2/3), and the time trade-off. Participants aged 11-19 years old were recruited from 5 transplantation centers in Australia. Mean scores were compared by using paired t tests, and linear multiple regression was used to define predictors for time trade-off QOL weights.

Results

Twenty-six adolescents participated in the study. On a scale with extremes of 0 (death) and 1 (full health), the participants had a mean (SD) time trade-off QOL weight of 0.99 ¡À 0.01 and HUI2/3 utility scores of 0.86 ¡À 0.16 and 0.85 ¡À 0.21, respectively. Time trade-off values were significantly higher than HUI Mark 2 values (P = .01) and HUI Mark 3 values (P = .02). From the HUI measure, decrements were observed in specific QOL domains, including vision, emotion (depression and anxiety), cognition, and pain.

Conclusion

Adolescent kidney transplant recipients had consistent and high values for their current QOL, which suggests that they perceive themselves to be close to full health. However, adequate emotional and cognitive support may improve their overall QOL.