Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes
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- 作者：Ji-Ann Lee1 ; Andrey Damianov2 ; Chia-Ho Lin2 ; Mariana Fontes1 ; Neelroop N. Parikshak3 ; Erik S. Anderson2 ; Daniel H. Geschwind3 ; Douglas L. Black2 ; 4 ; Kelsey C. Martin1 ; kcmartin@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Neuron
- 出版年：2016
- 出版时间：6 January 2016
- 年：2016
- 卷：89
- 期：1
- 页码：113-128
- 全文大小：2058 K
文摘
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Nuclear and cytoplasmic Rbfox1 isoforms regulate distinct neuronal mRNAs
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Cytoplasmic Rbfox1 regulates the stability and translation of its target mRNAs
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Rbfox1 and miRNA binding sites overlap significantly in target mRNA 3′ UTRs
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Cytoplasmic Rbfox1 targets are enriched in cortical development and autism genes