Decorin expression is decreased in first trimester placental tissue from pregnancies with small for gestation age infants at birth
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- 作者：P. Murthia ; b ; c ; e ; f ; padma.murthi@monash.edu" class="auth_mail" title="E-mail the corresponding author ; D.E. van Zantend ; J.J.H. Eijsinkd ; A.J. Borgb ; J.L. Stevensonb ; B. Kalionisa ; b ; A.K. Chuie ; f ; J.M. Saide ; f ; S.P. Brenneckea ; b ; J.J.H.M. Erwichd
- 关键词：Placenta ; Fatal growth restriction ; Small-for-gestation ; Decorin ; Proteoglycan ; Gene expression
- 刊名：Placenta
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：45
- 期：Complete
- 页码：58-62
- 全文大小：376 K
文摘
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Placental decorin (DCN) expression may contribute to the etiology of FGR.
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Small for gestation (SGA) is often used as a surrogate for FGR.
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First trimester placental tissues subsequently developed SGA was investigated.
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Placental DCN expression is significantly reduced in first trimester SGA at birth.
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A temporal relationship is observed for placental DCN expression and SGA.