Fe₃O₄ nanoparticles: As an efficient, green and magnetically reusable catalyst for the one-pot synthesis of 1,8-dioxo-decahydroacridine derivatives under solvent-free conditions

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• 作者：Mohammad Ali Ghasemzadeh ; Javad Safaei-Ghomi ; ^{safaei@kashanu.ac.ir} ; Halimeh Molaei
• 关键词：Fe3O4 ; 1 ; 8-dioxo-decahydroacridine ; Solvent-free ; Multicomponent reactions ; Nanoparticles ; Catalysts
• 刊名：Comptes Rendus Chimie
• 出版年：2012
• 出版时间：November-December, 2012
• 年：2012
• 卷：15
• 期：11-12
• 页码：969-974
• 全文大小：499 K

文摘

An efficient and environmentally friendly method for the one-pot synthesis of 1,8-dioxo-decahydroacridines has been developed in the presence of Fe₃O₄ nanoparticles. The multicomponent reactions of aldehydes, dimedone and amines were carried out under solvent-free conditions to obtain some 1,8-dioxo-9-aryl-10-aryl-decahydroacridine derivatives. The present approach provides several advantages including high yields, short reaction times, little catalyst loading and facile catalyst separation.