Effect of amitriptyline treatment on neurofilament-H protein in an experimental model of depression

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• 作者：Maria Domenica Sanna ; ^{maria.sanna@unifi.it} ; Carla Ghelardini ; Nicoletta Galeotti
• 关键词：NF-H ; phosphorylated heavy neurofilament subunit ; TST ; tail suspension test ; SPT ; sucrose preference test ; UCMS ; unpredictable chronic mild stress
• 刊名：Brain Research Bulletin
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：128
• 期：Complete
• 页码：1-6
• 全文大小：1225 K
• 卷排序：128

文摘

Cytoskeletal remodeling induced by amitriptyline in the CA3 region. Neuronal plasticity is a pharmacological target of amitriptyline. Hippocampal alterations of the p-NFH appeared associated with the mechanism of amitriptyline.