Domestic cats seropositive for Felis catus gammaherpesvirus 1 are often qPCR negative
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- 作者：Kathryn Stutzman-Rodrigueza ; kathrynroses@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Joel Rovnaka ; joel.rovnak@colostate.edu" class="auth_mail" title="E-mail the corresponding author ; Sue VandeWoudea ; sue.vandewoude@colostate.edu" class="auth_mail" title="E-mail the corresponding author ; Ryan M. Troyera ; b ; Ryan.Troyer@oregonstate.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：ELISA ; Herpesvirus ; Antibody ; Antigen ; Virus ; ORF52 ; ORF38 ; Prevalence ; Risk factor ; Feline
- 刊名：Virology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：498
- 期：Complete
- 页码：23-30
- 全文大小：4431 K
文摘
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FcaGHV1 is a newly described gammaherpesvirus that widely infects domestic cats.
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This study provides the first evidence of a host immune response against FcaGHV1.
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Cat antibody responses were detected against multiple recombinant FcaGHV1 antigens.
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Seroreactivity against FcaGHV1 ORF52 and ORF38 indicates 32% seroprevalence in USA.
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Approximately half of FcaGHV1 seropositive cats have detectable genome using qPCR.