Experimental microaneurysms in rats: I. Model for induction

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• 作者：Guerreiro ; Nilton Eduardo ; Colli ; Benedicto Oscar ; Carlotti Jr ; Carlos Gilberto ; Chimelli ; Leila
• 关键词：Experimental microaneurysms ; mechanical trauma ; aorta bifurcation ; rats
• 刊名：Surgical Neurology
• 出版年：2004
• 出版时间：November, 2004
• 年：2004
• 卷：62
• 期：5
• 页码：406-412
• 全文大小：275 K

文摘

Small aneurysms (lesser than 2 mm) in humans called sessile, baby aneurysms, or microaneurysms, generally are not able to be clipped or to be coil-packed through endovascular route. Among the modalities of treatment that have been used for treating microaneurysms, bipolar coagulation and wrapping of the lesion are outstanding. Nevertheless, demonstration of the efficacy of these treatments is difficult because most reported experimental models for inducting aneurysms are complex and difficult to be reproduced. This study aimed to develop a simple and reproducible model for inducing microaneurysms.