This was a cross-sectional study of HIV-infected, antiretroviral therapy-naïve adults in Zambia and Switzerland.
HIV/hepatitis B virus (HBV) co-infected patients are at least three times more likely to have significant liver fibrosis compared to HIV monoinfected individuals.
The association between HBV and liver fibrosis seems to be driven by HBV viral load.
The main risk factors for liver fibrosis are similar in Switzerland and Zambia.