- 作者：Emma Calabrese ; Francesca Zorzi ; Sara Onali ; Elisa Stasi ; Roberto Fiori ; Simonetta Prencipe ; Antonino Bella ; Carmelina Petruzziello ; Giovanna Condino ; Elisabetta Lolli ; Giovanni Simonetti ; Livia Biancone ; Francesco Pallone
- 关键词：IBD ; Inflammatory Bowel Disease ; Detection ; Cross-Sectional Imaging Technique ; Crohn's Disease
- 刊名：Clinical Gastroenterology and Hepatology
- 出版年：2013
- 出版时间：August, 2013
- 年：2013
- 卷：11
- 期：8
- 页码：950-955
- 全文大小：1899 K
Background & Aims
Small-intestine contrast ultrasonography (SICUS) is a radiation-free technique that can detect intestinal damage in patients with Crohn's disease (CD). We evaluated the diagnostic accuracy of SICUS in determining the site, extent, and complications of CD, compared with computed tomography (CT) enteroclysis as the standard.Methods
We performed a retrospective analysis of data from 59 patients with CD evaluated by SICUS and CT enteroclysis 3 months apart, between January 2007 and April 2012. We evaluated disease site (based on bowel wall thickness), extent of lesions, and presence of complications (stenosis, prestenotic dilation, abscess, or fistulas) using CT enteroclysis as the standard. Sensitivity, specificity, and diagnostic accuracy were calculated. We determined the correlations in maximum wall thickness and disease extent in the small bowel between results from SICUS and CT enteroclysis.
Results
SICUS identified the site of small bowel CD with 98 % sensitivity, 67 % specificity, and 95 % diagnostic accuracy; it identified the site of colon CD with 83 % sensitivity, 97.5 % specificity, and 93 % diagnostic accuracy. Results from SICUS and CT enteroclysis correlated in determination of bowel wall thickness (rho, 0.79) and disease extent (rho, 0.89; P < .0001 for both). SICUS detected ileal stenosis with 95.5 % sensitivity, 80 % specificity, and 91.5 % diagnostic accuracy, and prestenotic dilation with 87 % sensitivity, 67 % specificity, and 75 % diagnostic accuracy. SICUS detected abscesses with 78 % sensitivity, 100 % specificity, and 97 % diagnostic accuracy, and fistulas with 78.5 % sensitivity, 95.5 % specificity, and 91.5 % diagnostic accuracy.
Conclusions
SICUS identified lesions and complications in patients with CD with high levels of sensitivity, specificity, and accuracy compared with CT enteroclysis. SICUS might be used as an imaging tool as part of a focused diagnostic examination of patients with CD.