Brugada ECG disclosed by acute malaria: is it all about fever and propofol?

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• 作者：Marco Meggiolaro ; Aless ; ro Zorzi ; Mohamed El Maghawry ; Francesco Peruzza ; Federico Migliore ; Giovanni Maria Pittoni
• 关键词：Anesthesia ; cardiac ; Brugada syndrome ; Electrocardiographic abnormality ; Malaria
• 刊名：Journal of Clinical Anesthesia
• 出版年：September, 2013
• 年：2013
• 卷：25
• 期：6
• 页码：483-487
• 全文大小：1716 K

文摘

Brugada syndrome is an electrical cardiac disease predisposing to ventricular arrhythmias in which typical electrocardiographic (ECG) features consist of nonischemic repolarization abnormalities in the right precordial leads V1-V3. The appearance of a Brugada-ECG pattern is increasingly observed in critically ill patients and is traditionally attributed to the effect of body temperature and/or drug modulation on cardiac ion channels (鈥渁cquired Brugada syndrome鈥?. A patient with complicated malaria in whom Brugada-ECG abnormalities appeared in concomitance with fever and propofol administration is presented. The repolarization changes did not disappear until the patient鈥檚 clinical course improved.