A new complementary procedure for patients affected by head and neck cancer: Chemo-predictive assay
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- 作者：Antonio Cortesea ; 1 ; ancortese@unisa.it" class="auth_mail" title="E-mail the corresponding author ; Giuseppe Pantaleob ; 2 ; giuseppepantaleo88@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Massimo Amatoa ; 3 ; mamato@unisa.it" class="auth_mail" title="E-mail the corresponding author ; Logan Lawrencec ; 4 ; loganlawrence38@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Veronica Mayesd ; 5 ; Veronica.Mayes@chhi.org" class="auth_mail" title="E-mail the corresponding author ; Linda Brownd ; 6 ; lbrown@marshall.edu" class="auth_mail" title="E-mail the corresponding author ; Maria Rosaria Sarnoe ; f ; 7 ; mrsarno@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Jagan Vallurig ; 8 ; valluri@marshall.edu" class="auth_mail" title="E-mail the corresponding author ; Pier Paolo Claudio ; MD PhDe ; f ; 9 ; pclaudio@olemiss.edu" class="auth_mail" title="E-mail the corresponding author ; pclaudio@umc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Drug response assay ; Chemosensitivity assay ; ChemoID assay ; Cancer stem cells ; Oral cancer
- 刊名：International Journal of Surgery Case Reports
- 出版年：2016
- 出版时间：2016
- 年：2016
- 卷：26
- 期：Complete
- 页码：42-46
- 全文大小：731 K
文摘
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Cancer stem cells (CSCs) resist chemotherapy, thereby causing relapse of the disease.
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A new chemotherapy drug response assay (ChemoID), which measures the sensitivity of CSCs to a variety of chemotherapy agents has been developed.
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The ChemoID assay may assist an oncologist in making treatment decisions.
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The ChemoID procedure may lower treatment costs by eliminating ineffective chemotherapies and unnecessary toxicity.