Bovine 伪1-acid glycoprotein, a thermostable version of its human counterpart: Insights from Fourier transform infrared spectroscopy and in silico modelling
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- 作者：Maurizio Baldassarre ; Roberta Galeazzi ; Beatrice Maggiore ; Fabio Tanfani ; Andrea Scirè ; ; a.a.scire@univpm.it" class="auth_mail
- 关键词：伪1-acid glycoprotein ; FT-IR spectroscopy ; Thermostability ; Molten globule-like state ; Lipocalins ; Molecular dynamics
- 刊名：Biochimie
- 出版年：July 2014
- 年：2014
- 卷：102
- 期：Complete
- 页码：19-28
- 全文大小：1617 K
文摘
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Bovine 伪1-acid glycoprotein is much more thermostable than human 伪1-acid glycoprotein.
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A homology model of bovine 伪1-acid glycoprotein has been obtained.
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Inspection of the model explains the high thermostability.
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As in other lipocalins, a molten globule state has been observed.