Increased alloreactivity and adverse outcomes in obese kidney transplant recipients are limited to those with diabetes mellitus

详细信息    查看全文

• 作者：Thomas Schachtner^a ; ^b ; ^c ; ^{thomas.schachtner@charite.de} ; Maik Stein^b ; Petra Reinke^a ; ^b
• 关键词：BMI ; body mass index ; eGFR ; estimated glomerular filtration rate ; KTRs ; kidney transplant recipients ; NODAT ; new-onset diabetes after transplantation
• 刊名：Transplant Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：40
• 期：Complete
• 页码：8-16
• 全文大小：1093 K
• 卷排序：40

文摘

Obese KTRs show a high incidence of pre-existing diabetes mellitus. Outcomes of obese diabetic KTRs are inferior to obese non-diabetic KTRs. Obese non-diabetic KTRs show comparable outcomes with non-obese KTRs. Obese diabetic KTRs show higher frequencies of preformed donor-reactive T-cells.