β-(1 → 3,1 → 6)-d-glucans produced by Diaporthe sp. endophytes: Purification, chemical characterization and antiproliferative activity against MCF-7 and HepG2-C3A cells
刊名:International Journal of Biological Macromolecules
出版年:2017
出版时间:January 2017
年:2017
卷:94
期:part_PA
页码:431-437
全文大小:971 K
卷排序:94
文摘
β-glucans (EPS-P) were purified from the fermentation broth of two Diaporthe endophytes. β-glucans consisted of a main chain of glucopyranosyl (1 → 3) linkages substituted at O-6 by glucosyl residues. EPS-PD2 inhibited up to ∼75% of the proliferation of MCF-7 cells. Both glucans inhibited up to ∼84% of the proliferation of HepG2-C3A cells.