Molecular characterization and expression analysis of glucokinase from herbivorous fish Megalobrama amblycephala subjected to a glucose load after the adaption to dietary carbohydrate levels
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- 作者：Xiang-Fei Li ; Chao Xu ; Ding-Dong Zhang ; Guang-Zhen Jiang ; Wen-Bin Liu ; wbliu@njau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Megalobrama amblycephala ; Glucokinase ; Molecular cloning ; Glucose load ; Dietary carbohydrate
- 刊名：Aquaculture
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：459
- 期：Complete
- 页码：89-98
- 全文大小：3597 K
文摘
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A full-length cDNA coding GK was characterized in herbivorous M. amblycephala.
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It shares a high degree of conservation among most fish and higher vertebrates.
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Glucose load resulted in a prompt increase of hepatic GK expression.
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High dietary carbohydrate induced an up-regulation of GK expression and activity.