Ultra-miniaturization of a planar amperometric sensor targeting continuous intradermal glucose monitoring
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- 作者：Federico Ribet ; ribet@kth.se ; Gö ; ran Stemme ; Niclas Roxhed
- 关键词：Glucose biosensor ; MEMS ; Diabetes ; Continuous glucose monitoring ; Amperometry ; Iridium oxide reference electrode
- 刊名：Biosensors and Bioelectronics
- 出版年：2017
- 出版时间：15 April 2017
- 年：2017
- 卷：90
- 期：Complete
- 页码：577-583
- 全文大小：629 K
- 卷排序：90
文摘
The smallest fully integrated planar glucose sensor area up-to-date is reported. Microfabricated devices based on enzymatic electrochemical glucose sensing are shown. A dynamic, linear and selective amperometric sensor has been characterized in-vitro. A miniaturization sufficient to perform CGM in the dermis can be achieved. Iridium oxide reference electrodes provide stability under physiological conditions.