Structural characterization of an intestinal immune system-modulating arabino-3,6-galactan-like polysaccharide from the above-ground part of Astragalus membranaceus (Bunge)
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- 作者：Jung Dae Lima ; Chang Yeon Yuc ; Seung Hyun Kimb ; Ill Min Chungb ; imcim@konkuk.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：RA ; Radix Astragali ; RAP ; polysaccharide fraction of Radix Astragali ; T-cell ; T lymphocyte ; LAK ; lymphokine-activated killer ; IL-2 ; interleukin 2 ; β-d-Galp ; β-d-galactopyranoside ; α-l-Araf ; α-l-arabinofuranoside ; α-l-Arap ; α-l-arabinopyranoside ; α-l-Rhap ; α-l-rhamnopyranose ; β-d-Glcp ; β-d-glucopyranoside ; β-d-GlcpA ; β-d-glucosyluronic acid ; Ara ; arabinose ; Gal ; galactose ; Glu ; glucose ; Man ; mannose ; GALT ; gut-associated lymphoreticular tissues ; IgA ; immunoglobulin A ; AFase ; exo-α-l-arabinofurano
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 January 2016
- 年：2016
- 卷：136
- 期：Complete
- 页码：1265-1272
- 全文大小：1080 K
文摘
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Arabino-3,6-galactan (AMA-1-b-PS2)-like polysaccharide was isolated from above-ground parts of Astragalus membranaceus (Bunge).
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Structure of AMA-1-b-PS2 was characterized by sequential enzyme digestion with exo-α-l-arabinofuranosidase and exo-β-d-(1 → 3)-galactanase.
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AMA-1-b-PS2 has β-d-(1 → 3)-galactan branched side-chains of β-d-(1 → 3,6)-galactan structures, comprised mainly of 6-linked galactose.
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AMA-1-b-PS2 modulates the gastric mucosal and systemic immune system.