Determination of ethyl glucuronide in human hair samples: A multivariate analysis of the impact of extraction conditions on quantitative results

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• 作者：Alexander Mueller^a ; ^{al.mueller@uke.de} ; Hilke Jungen^a ; Stefanie Iwersen-Bergmann^a ; Lars Raduenz^a ; Susanne Lezius^b ; Hilke Andresen-Streichert^a
• 关键词：Alcohol biomarkers ; Hair testing ; Mass spectrometry ; Ethyl glucuronide
• 刊名：Forensic Science International
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：271
• 期：Complete
• 页码：43-48
• 全文大小：1279 K
• 卷排序：271

文摘

There is a strong impact of extraction conditions on recovery of EtG from human hair. Six experimental factors are investigated using a chemometric approach. Extraction solvent and temperature are of superior importance. A harmonized extraction protocol should reduce interlaboratory variabilities