Anti-obesity effect of Crinum asiaticum var. japonicum Baker extract in high-fat diet-induced and monogenic obese mice
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- 作者：Yong Joon Jeonga ; 1 ; Eun-Hwa Sohnb ; Yong-Hwan Jungc ; 1 ; Weon-Jong Yoond ; Young Mi Choa ; Inhye Kima ; Sung Ryul Leee ; lsr1113@inje.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Se Chan Kanga ; sckang@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：CAE ; Crinum asiaticum var. japonicum Baker extract ; aP2 ; adipocyte protein 2 ; ACC ; acetyl CoA carboxylase ; C/EBP ; CCAAT/enhancer binding protein ; FAS ; fatty acid synthase ; HDL-C ; high density lipoprotein-cholesterol ; HMGCR ; 3-hydroxy-3-methyl-glutaryl-CoA reductase ; LDL-C ; low density lipoprotein-cholesterol ; LPL ; lipoprotein lipase ; PPARγ ; peroxisome proliferator-activated receptor γ ; TC ; total cholesterol ; TG ; triglyceride
- 刊名：Biomedicine & Pharmacotherapy
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：82
- 期：Complete
- 页码：35-43
- 全文大小：1429 K
文摘
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CAE showed strong potential against adipocyte differentiation and lipogenesis.
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10">Genes associated with adipocyte differentiation and lipogenesis were inhibited by CAE.
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15">CAE showed an anti-obesity effect in diet-induced and monogenic obese mice.