Phylogenetic characterization of Clonorchis sinensis proteins homologous to the sigma-class glutathione transferase and their differential expression profiles
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- 作者：Young-An Baea ; 1 ; Jeong-Geun Kimb ; 1 ; Yoon Kongb ; kongy@skku.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：C-H2O2 ; cumene hydroperoxide ; CDS ; coding DNA sequence ; ESP ; excretory-secretory products ; GSH ; reduced glutathione ; GST ; glutathione transferase ; I-3-C ; indole-3-carbinol ; MAPEG ; membrane-associated proteins in eicosanoid and glutathione metabolism ; PB ; piperonyl butoxide ; PG ; prostaglandin ; PGDS ; PGD synthase ; PGS ; PG synthase
- 刊名：Molecular & Biochemical Parasitology
- 出版年：2016
- 出版时间：March-April 2016
- 年：2016
- 卷：206
- 期：1-2
- 页码：46-55
- 全文大小：4712 K
文摘
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The phylogeny of GSTs encoded by the Clonorchis sinensis genome was investigated.
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10">C. sinensis harbors 12 cytosolic, mitochondrial, and microsomal GST families.
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15">The transcriptional profile of excretory GSTs was assessed upon oxidative stimuli.
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The mu-/sigma-GSTs might have specialized or coordinated to regulate redox potential.