Glycyrrhizin ameliorates oxidative stress and inflammation in hippocampus and olfactory bulb in lithium/pilocarpine-induced status epilepticus in rats
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- 作者：Susana Gonzá ; lez-Reyesa ; Juan Jair Santillá ; n-Cigalesa ; Angé ; lica Saraí ; Jimé ; nez-Osoriob ; José ; Pedraza-Chaverrib ; Rosalinda Guevara-Guzmá ; na ; rguevara@unam.mx" class="auth_mail" title="E-mail the corresponding author
- 关键词：Status epilepticus ; Inflammation ; Oxidative stress ; Hippocampus ; Olfactory bulb ; Glycyrrhizin
- 刊名：Epilepsy Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：126
- 期：Complete
- 页码：126-133
- 全文大小：1352 K
文摘
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GL prevents oxidative stress after status epilepticus in the hippocampus and olfactory bulb.
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Pretreatment with GL increases antioxidant enzyme activity in the hippocampus.
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GL preserves enzyme activities in the olfactory bulb.
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GL decreases inflammation in the hippocampus and olfactory bulb after status epilepticus.