Spectroscopic and molecular dynamics characterization of glycyrrhizin membrane-modifying activity
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- 作者：O.Yu. Selyutinaa ; b ; olga.gluschenko@gmail.com" class="auth_mail" title="E-mail the corresponding author ; I.E. Apanasenkoa ; b ; A.V. Kima ; E.A. Shelepovaa ; b ; S.S. Khalikovc ; N.E. Polyakova
- 关键词：Glycyrrhizic acid ; Liposome ; Lipid bilayer ; Membrane permeability ; Drug delivery ; Nuclear magnetic resonance ; Molecular dynamics
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：147
- 期：Complete
- 页码：459-466
- 全文大小：2935 K
文摘
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Glycyrrhizic acid (GA) incorporates into lipid bilayer.
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Incorporation of GA leads to decrease in lipid mobility.
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GA forms pores in lipid bilayer.