In situ one-pot preparation of superparamagnetic hydrophilic porous microspheres for covalently immobilizing penicillin G acylase to synthesize amoxicillin
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- 作者：Ping Xue ; Yaohua Gu ; Weiguang Su ; weiguangsu@nxu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Huihui Shuai ; Julan Wang
- 关键词：In situ one-pot synthesis ; Fe3O4-GMH microspheres ; Formamide ; Immobilized penicillin G acylase ; Amoxicillin synthesis
- 刊名：Applied Surface Science
- 出版年：2016
- 出版时间：30 January 2016
- 年：2016
- 卷：362
- 期：Complete
- 页码：427-433
- 全文大小：3346 K
文摘
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Fe3O4-GMH was successfully in situ one-pot synthesized for the first time.
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The amount of formamide played a fairly important role in the morphology of Fe3O4-GMH.
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Fe3O4-GMH was a highly efficient carrier for immobilizing PGA to synthesize amoxicillin.
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PGA/Fe3O4-GMH had an excellent operational stability.