Bioconcentration, metabolism, and biomarker responses in marine medaka (Oryzias melastigma) exposed to sulfamethazine
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- 作者：Songhe Zhao<sup>asup> ; Xinhong Wang<sup>asup><sup> ; sup><sup>xhwang@xmu.edu.cn" class="auth_mail" title="E-mail the corresponding authorsup> ; Yongyu Li<sup>asup> ; Jianqing Lin<sup>bsup>
- 关键词：SM2 ; sulfamethazine ; N-SM2 ; acetylated sulfamethazine ; BCF ; bioconcentration factor ; BAFs ; bioaccumulation factors ; SOD ; superoxide dismutase ; CAT ; catalase ; UPLC ; ultra-performance liquid chromatography ; MS ; mass spectrometry ; MDL ; method detection limits ; LOD ; limit of detection ; LOQ ; limit of quantification ; SPE ; solid phase extraction
- 刊名：Aquatic Toxicology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：181
- 期：Complete
- 页码：29-36
- 全文大小：803 K
文摘
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Sulfamethazine (SM<sub>2sub>) bioaccumulation in different organs of maine medaka.
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SM<sub>2sub> accumulated in gonad tissue, N-SM<sub>2sub> major accumulated in goad tissue.
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SOD and CAT activity responded.
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Gender-related differences were also observed.
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Make an assumption about the upake process by marine medaka.