Placental site trophoblastic tumors and epithelioid trophoblastic tumors: Biology, natural history, and treatment modalities

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• 作者：Neil S. Horowitz ; MD ; Donald P. Goldstein ; MD ; Ross S. Berkowitz ; MD ; ^{rberkowitz@partners.org}
• 关键词：Gestational trophoblastic neoplasia ; Placental site trophoblastic tumor ; Epithelioid trophoblastic tumor
• 刊名：Gynecologic Oncology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：144
• 期：1
• 页码：208-214
• 全文大小：830 K
• 卷排序：144

文摘

PSTT and ETT are rare types of GTN that arise from intermediate trophoblast. Time from antecedent pregnancy > 4 years and advanced stage are poor prognostic factors. Hysterectomy is the primary treatment for stage I disease. Stage I disease with high-risk features and all advanced stage disease require chemotherapy. EMA-EP and TP/TE are the chemotherapy regimens recommended for treatment of PSTT and ETT.