Modeling tumor microenvironments using custom-designed biomaterial scaffolds
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- 作者：Zen Liu1 ; Gordana Vunjak-Novakovic1 ; 2 ; gv2131@columbia.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Current Opinion in Chemical Engineering
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：11
- 期：Complete
- 页码：94-105
- 全文大小：3097 K
文摘
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The tumor microenvironment regulates tumor initiation, progression, and metastasis.
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We summarize the use of biomaterials in tumor modeling in vitro.
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Engineered tumor models are becoming increasingly complex and heterotypic.
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Insights into drug resistance may inform the development of novel therapeutic targets.