刊名:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
出版年:2017
出版时间:January 2017
年:2017
卷:1864
期:1
页码:1-11
全文大小:1665 K
卷排序:1864
文摘
γ2-Herpesviral GPCR constitutively activates T cells. γ2-Herpesviral GPCR physically interacts with cellular CXCR4. CXCR4 silencing abolishes T cell activation by γ2-herpesviral GPCR. T cell activation by vGPCR is independent of proximal TCR signaling molecules.