刊名:Biochimica et Biophysica Acta (BBA) - Biomembranes
出版年:2017
出版时间:February 2017
年:2017
卷:1859
期:2
页码:268-281
全文大小:2654 K
卷排序:1859
文摘
Simulations detect interactions between cholesterol and GPCRs deep in the membrane. These interactions change on agonist binding. Requirements for interaction are just a hydrogen bond partner and a hole or cleft. These interactions represent a new way in which cholesterol could affect membrane protein function.