Surgical Accuracy of 3-Tesla Versus 7-Tesla Magnetic Resonance Imaging in Deep Brain Stimulation for Parkinson Disease

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• 作者：Peter Jan van Laar¹ ; D.L. Marinus Oterdoom² ; Gert J. ter Horst³ ; Arjen L.J. van Hulzen¹ ; Eva K.L. de Graaf² ; Hans Hoogduin⁴ ; Linda C. Meiners¹ ; J. Marc C. van Dijk² ; ^{j.m.c.van.dijk@umcg.nl" class="auth_mail" title="E-mail the corresponding author}
• 关键词：7-Tesla MRI ; Accuracy ; Deep brain stimulation ; Parkinson disease
• 刊名：World Neurosurgery
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：93
• 期：Complete
• 页码：410-412
• 全文大小：586 K

文摘

In deep brain stimulation (DBS), accurate placement of the lead is critical. Target definition is highly dependent on visual recognition on magnetic resonance imaging (MRI). We prospectively investigated whether the 7-T MRI enabled better visualization of targets and led to better placement of leads compared with the 1.5-T and the 3-T MRI.

Methods

Three patients with PD (mean, 55 years) were scanned on 1.5-, 3-, and 7-T MRI before surgery. Tissue contrast and signal-to-noise ratio were measured. Target coordinates were noted on MRI and during surgery. Differences were analyzed with post-hoc analysis of variance.

Results

The 7-T MRI demonstrated a significant improvement in tissue visualization (P < 0.005) and signal-to-noise ratio (P < 0.005). However, no difference in the target coordinates was found between the 7-T and the 3-T MRI.

Conclusions

Although the 7-T MRI enables a significant better visualization of the DBS target in patients with PD, we found no clinical benefit for the placement of the DBS leads.