A study of cell proliferation using immunohistological staining: A case report of congenital granular cell epulis

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• 作者：Bo Zhang^a ; ^b ; ^{michaelbozhang@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Xiaodan Tan^b ; Kunlun Zhang^b ; Yanchun Li^c ; Jingjing Chen^d ; Feng Zhang^e
• 关键词：Congenital granular cell epulis ; Infant ; Labeling indexes ; Ki-67 ; PCNA
• 刊名：International Journal of Pediatric Otorhinolaryngology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：88
• 期：Complete
• 页码：58-62
• 全文大小：1610 K

文摘

An unusual case of a 1-day-old Chinese female neonate with a solid tumor mass in the maxillary anterior ridge of the edentulous jaw is reported. Based on the clinical and histopathological features, the diagnosis was of obstructive congenital granular cell epulis (CGCE) which is an uncommon benign tumor that preferentially develops in female infants. Immunohistochemical analysis of the lesion was performed and the rate of cell proliferation was determined by immunostaining with Ki-67 and PCNA, which showed labeling indexes of 11.1% and 33.3%, respectively. No recurrence was observed in the follow-up.