Mucosal immunization confers long-term protection against intragastrically established Neospora caninum infection

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• 作者：Pedro Ferreirinha^a ; ^b ; Alexandra Correia^a ; ^b ; Maria Teixeira-Coelho^b ; Hugo Osó ; rio^a ; ^c ; ^e ; Luzia Teixeira^d ; ^f ; Antó ; nio Rocha^d ; Manuel Vilanova^a ; ^b ; ^d ; ^{vilanova@icbas.up.pt}
• 关键词：NcMP ; Neospora caninum membrane proteins ; NcS ; N. caninum sonicates ; NcHsp70 ; N. caninum heat shock protein 70 ; NcGRA7 ; N. caninum dense granule antigen 7 ; NcMIC1 ; N. caninum microneme associated protein 1 ; i.n. ; intranasal ; i.g. ; intragastric ; ILF ; intestinal lavage fluids ; VLF ; vaginal lavage fluids
• 刊名：Vaccine
• 出版年：2016
• 出版时间：7 December 2016
• 年：2016
• 卷：34
• 期：50
• 页码：6250-6258
• 全文大小：1470 K
• 卷排序：34

文摘

Intranasal immunization confers long-term protection against neosporosis. Antigen-specific intestinal IgA production was sustained in the long term. Dense granule antigen 7 and microneme associated protein 1 were immunodominant.