Les entérobactéries isolées d'infections urinaires en pratique de ville : étude AFORCOPIBIO 1995
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- 作者：D. De Mouy ; J.D. Cavallo ; R. Fabre ; E. Garrabe ; F. Grobost ; M. Armengaud ; R. Labia ; les membres de l'Aforcopibio
- 关键词：Enterobacteriaceae ; Urinary tract infections ; Antibiotics ; Survey
- 刊名：Médecine et Maladies Infectieuses
- 出版年：1997
- 出版时间：June 1997
- 年：1997
- 卷：27
- 期：Supplement 6
- 页码：642-645
- 全文大小：303 K
文摘
A prospective multicenter study was performed during two months (May and June 1995) by ten private clinical laboratories which collected 700 Enterobacteriaceae in 849 patients with community acquired urinary tract infection. Isolated E. coli rate (70.2 % ) was the same as in 1990. Susceptibility to amoxicillin, amoxicillin-clavulanic acid, and cotrimoxazole had decreased. Susceptibility to fluoroquinolons, third generation cephalosporins, and fosfomycin remained stable. Among 178 E. coli cases, decreased susceptibility to aminopenicillin was mainly due to penicillinase (TEM-1: 86.5 % ; TEM-2: 1.7 % , OXA: 1.7 % and TRI: 5.7 % ) and in the other cases to the hyperproduction of cephalosporinase (2.8 % ), combined cephalosporinase + penicillinase (0.6 % ). P. mirabilis resistant strains expressed penicillinase TEM-1 in five cases and TEM-2 in three cases. Among 53 other Enterobacteriaceae, 4 out of 18 K. Pneumoniae produced an extended spectrum β-lactamase (SHV-2 enzyme) and 7 out of 25 Enterobacteriaceae overproduced their chromosomal cephalosporinase.