Body mass index reference charts for the individuals with Down syndrome aged 2‐18 years

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• 作者：Fabio Bertapelli^a ; ^{fbertapelli@gmail.com} ; Maira R. Machado^a ; Raí ; sa do Val Roso^a ; Gil Guerra‐Jú ; nior^b
• 关键词：Trisomy 21 ; Body mass index ; Weight ; Height ; Growth charts ; Nutritional status
• 刊名：Jornal de Pediatria (Versão em Português)
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：93
• 期：1
• 页码：94-99
• 全文大小：1288 K
• 卷排序：93

文摘

To develop Brazilian growth charts for body mass index (BMI‐for‐age) for individuals with Down syndrome (DS). The secondary objective was to compare the BMI‐for‐age with the Centers for Disease Control and Prevention standards (CDC).MethodsA retrospective and cross‐sectional growth study of 706 youth with DS (56.7% males) was performed in 51 centers in São Paulo state, Brazil. Weight and height were used to calculate the BMI (kg/m2). The LMS method was applied to construct the growth charts. Z‐scores were based on the CDC 2000 growth standards.ResultsThe BMI‐for‐age reference charts showed excellent goodness of fit statistics for boys and girls with DS aged 2–18 years. At 2 years of age, the mean BMI Z‐scores of boys and girls with DS were lower compared to those of the CDC (Z‐score = −0.2). In contrast, children with DS aged 3‐18 years had higher mean Z‐scores for BMI‐for‐age when compared to those of the CDC (Z‐scores = +0.2 to +1.3).ConclusionsThe BMI of Brazilian youth with DS differs from those references established by CDC. These are the first Brazilian BMI‐for‐age charts for individuals with DS and will hopefully guide clinicians and parents in the evaluation and management of the nutritional status in children and adolescents with DS in Brazil.