Genotoxicity and cytotoxicity assessment of new ethyl-carbamates with ixodicidal activity
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- 作者：Marí ; a Guadalupe Prado-Ochoaa ; mgpo1@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Marco Antonio Muñ ; oz-Guzmá ; na ; mmunoz74@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Ví ; ctor Hugo Vá ; zquez-Valadezb ; hugounam83@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ana Marí ; a Velá ; zquez-Sá ; nchezb ; velzquezanamara@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ana Marí ; a Salazarc ; anamsm@biomedicas.unam.mx" class="auth_mail" title="E-mail the corresponding author ; Patricia Ramí ; rez-Nogueraa ; ramireznoguera@unam.mx" class="auth_mail" title="E-mail the corresponding author ; Enrique Angelesb ; eupirne@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Fernando Alba-Hurtadoa ; fealba@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Carbamates ; Rhipicephalus microplus ; Mitotic index ; Micronucleus ; Anti-tick activity
- 刊名：Mutation Research/Genetic Toxicology and Environmental Mutagenesis
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：807
- 期：Complete
- 页码：8-14
- 全文大小：1279 K
文摘
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The genotoxic and cytotoxic potential of two ethyl-carbamates proposed as new ixodicides was evaluated.
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Ethyl-carbamates increased the frequency of micronucleated polychromatic erythrocytes.
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The ethyl-carbamates have cytostatic effects in human lymphocytes.