Synthesis of a fluorogenic probe for thiols based on a coumarin schiff base copper complex and its use for the detection of glutathione

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• 作者：Guangjie He ; ^{guangjiehe@163.com} ; Jing Li ; Zhongquan Wang ; Chenxi Liu ; Xiangli Liu ; Liguo Ji ; Chenyan Xie ; Qingzhi Wang ; ^{wqzmgl@126.com}
• 关键词：Fluorogenic probe ; Coumarin ; Thiols ; Glutathione ; Cell imaging
• 刊名：Tetrahedron
• 出版年：2017
• 出版时间：19 January 2017
• 年：2017
• 卷：73
• 期：3
• 页码：272-277
• 全文大小：946 K
• 卷排序：73

文摘

A coumarin schiff base Cu2+ complex acting as fluorogenic chemodosimeter for thiols was prepared. The fluorogenic probe has a better ability to distinguish GSH and Cys/Hcy. The probe could be used for fluorescence imaging of glutathione in living cells.