Optimized Approaches for Generation of Integration-free iPSCs from Human Urine-Derived Cells with Small Molecules and Autologous Feeder
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- 作者：Di Li1 ; Linli Wang2 ; Jundi Hou2 ; Qun Shen1 ; Qianyu Chen2 ; Xiaoshan Wang2 ; Juan Du2 ; Xiujuan Cai2 ; Yongli Shan2 ; Tian Zhang2 ; Tiancheng Zhou2 ; Xi Shi2 ; Yuhua Li1 ; liyuhua2011gz@163.com" class="auth_mail" title="E-mail the corresponding author ; Hua Zhang1 ; jimzhua@163.com" class="auth_mail" title="E-mail the corresponding author ; Guangjin Pan2 ; pan_guangjin@gibh.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：CPFT-a ; P53 ; small molecules ; autologous UC feeders ; hUCs ; iPSCs
- 刊名：Stem Cell Reports
- 出版年：2016
- 出版时间：10 May 2016
- 年：2016
- 卷：6
- 期：5
- 页码：717-728
- 全文大小：1497 K
文摘
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SM treatment significantly enhances the reprogramming of hUCs
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Replacement of Matrigel with autologous hUCs as feeder facilitates reprogramming
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Selection of cell-dependent reprogramming strategy is useful for banking iPSC lines