Exploring the substrate scope of mutants derived from the robust alcohol dehydrogenase TbSADH
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- 作者：Zhoutong Sun&dagger ; ; Guangyue Li&dagger ; ; Adriana Ilie&dagger ; ; Manfred T. Reetz ; reetz@mpi-muelheim.mpg.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Enantioselectivity ; Alcohol dehydrogenase ; Asymmetric ketone reduction ; Biocatalysis ; Directed evolution
- 刊名：Tetrahedron Letters
- 出版年：2016
- 出版时间：10 August 2016
- 年：2016
- 卷：57
- 期：32
- 页码：3648-3651
- 全文大小：673 K
文摘
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Wide substrate scope of alcohol dehydrogenase mutants in asymmetric ketone reduction.
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Thermostable alcohol dehydrogenase mutants in enantioselective ketone reduction.
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Mild stereoselective biocatalysts as an alternative to chiral man-made Ru-catalysts.