Role of synbiotics in polysaccharide assisted colon targeted microspheres of mesalamine for the treatment of ulcerative colitis

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• 作者：Rupinderjeet Kaur ; Monica Gulati ; ^{monicagulati14@gmail.com} ; Sachin Kumar Singh
• 关键词：Mesalamine ; Microspheres ; Guar gum ; Xanthan gum ; Probiotics ; Co-administration
• 刊名：International Journal of Biological Macromolecules
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：95
• 期：Complete
• 页码：438-450
• 全文大小：2989 K
• 卷排序：95

文摘

Mesalamine microspheres was formulated using guar and xanthan gum. Developed formulation was able to target the drug to colon. Co-administration of probiotics with the formulation was evaluated. Co-administration of probiotics was found to give better therapeutic effect.