“Aerogels of enzymatically oxidized galactomannans from leguminous plants: Versatile delivery systems of antimicrobial peptides and enzymes”

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• 作者：Paola Campia^a ; ^{paola.campia@ispa.cnr.it} ; Erika Ponzini^b ; ^{erika.ponzini@unimib.it} ; Bianca Rossi^d ; ^{bianca.rossi@polimi.it} ; Stefano Farris^c ; ^{stefano.farris@unimi.it} ; Tiziana Silvetti^a ; ^{tiziana.silvetti@ispa.cnr.it} ; Luca Merlini^d ; ^{luca.merlini@icrm.cnr.it} ; Milena Brasca^a ; ^{milena.brasca@ispa.cnr.it} ; Rita Grandori^b ; ^{rita.grandori@unimib.it} ; Yves M. Galante^d ; ^{yves.galante@icrm.cnr.it} ; ^{galante.yves@gmail.com}
• 关键词：ABTS ; 2 ; 2&prime ; -azino-bis(3-ethyl-benzothiazoline-6-sulphonic acid) ; CFU ; colony forming unit ; CNF ; cellulose nanofibrillated ; DS ; delivery system ; EOLFG ; enzymatically oxidized lyophilized fenugreek gum ; EOLGG ; enzymatically oxidized lyophilized guar gum ; EOLSG ; enzymatically oxidized lyophilized sesbania gum ; FG ; fenugreek gum ; GG ; guar gum ; GO ; galactose oxidase ; Lcc ; laccase ; LFG ; lyophilized fenugreek gum ; LGG ; lyophilized guar gum ; LMS ; laccase mediator system ; LSG ; lyophilized sesbania g
• 刊名：Carbohydrate Polymers
• 出版年：2017
• 出版时间：20 February 2017
• 年：2017
• 卷：158
• 期：Complete
• 页码：102-111
• 全文大小：1369 K
• 卷排序：158

文摘

Aerogels were obtained by lyophilization of laccase-oxidized galactomannans (GM). GM’s were from: fenugreek, sesbania and guar, with decreasing galactose content. The mechanical properties and porosity of these aerogels were studied. Sesbania and guar yielded similar aerogels, while fenugreek a more stable one. They were all evaluated as delivery systems (DS) of absorbed and released actives. The actives tested were: polymyxin B, nisin, lysozyme, a protease and a lipase. These biomaterials could be developed as biocompatible DS of active principles.