Casearin D inhibits ERK phosphorylation and induces downregulation of cyclin D1 in HepG2 cells

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• 作者：Guilherme &Aacute ; lvaro Ferreira-Silva^a ; ¹ ; Carla Carolina Lopes Lages^b ; ¹ ; Patricia Sartorelli^c ; Fl&aacute ; via Rie Hasegawa^c ; Marisi Gomes Soares^b ; ; Marisa Ionta^a ; ^{marisaionta@gmail.com}
• 关键词：Hepatocellular carcinoma ; Cell cycle arrest ; Cyclin D1 expression ; Casearins ; Casearia sylvestris
• 刊名：Toxicology in Vitro
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：38
• 期：Complete
• 页码：27-32
• 全文大小：537 K
• 卷排序：38

文摘

Casearin D inhibits cell cycle progression of HepG2 cells. Casearin D treatment reduces ERK phosphorylation levels in HepG2 cells. Cyclin D1 expression is reduced in HepG2 cells after treatment with Casearin D.