0503: Asymptomatic carotid stenosis in patient with acute coronary syndrome: who should be screened?

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• 作者：Audrey Agullo ; ⁽¹⁾ ; ^{audrey.agullo@freesbee.fr" class="auth_mail" title="E-mail the corresponding author} ; Michel Dauzat⁽²⁾ ; Iris Schuster⁽²⁾ ; Guillaume Cayla⁽²⁾ ; Gudrun Boge⁽²⁾ ; Thomas Vacter⁽²⁾ ; Myriam Akodad⁽²⁾ ; Marion Berous⁽²⁾ ; Jean-Christophe Macia⁽²⁾ ; Florence Leclercq⁽²⁾
• 刊名：Archives of Cardiovascular Diseases Supplements
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：8
• 期：1
• 页码：82
• 全文大小：109 K

文摘

While prevalence and risk factors of carotid stenosis in acute coronary sydrome (ACS) are under investigated, we evaluated patients admitted in our intensive care unit for an ACS in order to define if a screening of this population would be relevant.

Methods

Systematic carotid Doppler ultrasound screening was done on 102 consecutive patients admitted to the intensive care unit after an ACS with or without ST elevation. Degree of stenosis was determined using NASCET and hemodynamic critera. Clinical data and risk factors of atherosclerosis were collected for all patients. The Chi square test was used for categorical variables and ordinal variables were analyzed using Wilcoxon or Student’s tests.

Results

Fifty-two percent of patient (n=53) had at least one carotid stenosis. Mild stenosis (<50%) concerned 45 patients (44%) while 6 patients (6%) had moderate (50-69%) stenosis and 2 patients (2%) had severe (>70%) stenosis. As shown is the table, on univariate analysis, the only predictive factors of moderate and severe stenosis were age >75years (OR=11.8; p=0,016), diabetes mellitus (OR=3.9; p=0,05), history of myocardial infarction (OR=11.4; p=0,002) and left ventricular ejection fraction  <40% (OR=6.6; p=0,007).