Repeatability of health economic data in COPD

详细信息    查看全文

• 作者：Rune Nielsen ; Ane Johannessen ; Hege Marie Schnelle ; Per S. Bakke ; Jan E. Askildsen ; Ernst R. Omenaas ; Amund Gulsvik
• 关键词：Healthcare costs ; Chronic obstructive pulmonary disease ; Reproducibility of results ; Repeatability ; Reliability
• 刊名：Respiratory Medicine
• 出版年：2008
• 出版时间：November 2008
• 年：2008
• 卷：102
• 期：11
• 页码：1556-1562
• 全文大小：230 K

文摘

Summary

Background

Little is known concerning the precision of self-reported health economic data.

Aim

To investigate the repeatability of self-reported health economic cost and utilization data in subjects with chronic obstructive pulmonary disease (COPD).

Methods

Twelve weeks after inclusion, a physician and a nurse in random order interviewed 29 subjects with post-bronchodilator COPD included from a research registry of COPD patients. The interview recorded healthcare utilization and costs, sick leave, exacerbations and quality of life (QoL). Variation of individual agreement of observations was described estimating kappa statistics and 95 % limits of agreement.

Results

Mean age was 63 years (standard deviation (SD) 10) and 17 participants were men. Average FEV₁ % predicted was 56 % (SD 15). For sick leave, exacerbation, healthcare provider visit, change of medication, assistance and leisure time the kappa values were 1.00, 0.73, 0.73, 0.66, 0.63 and 0.54, respectively. The physician recorded fewer days of exacerbation and fewer contacts with healthcare providers than the nurse (p = 0.01 and p = 0.05, respectively). The 95 % limits of agreement for costs of drugs were −690 to +710 Norwegian Kroner (NOK), −1200 to +899 NOK for costs of healthcare providers and −20 to +26 for QoL as measured by a visual analogue scale.

Conclusion

Repeatability of economic data from COPD patients showed considerable variation. This issue should be addressed when analyzing cost data from interviews and when designing studies on health economy.