Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome
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- 作者：Valerie M. Harrisa ; b ; Rohan Sharmac ; d ; Joshua Cavetta ; c ; Biji T. Kuriena ; c ; d ; Ke Liue ; f ; Kristi A. Koelscha ; c ; d ; Astrid Rasmussena ; Lida Radfarg ; David Lewisg ; Donald U. Stoneh ; C. Erick Kaufmanc ; Shibo Lii ; Barbara Segalj ; Daniel J. Wallacek ; Michael H. Weismank ; Swamy Venuturupallik ; Jennifer A. Kellya ; Marta E. Alarcon-Riquelmea ; l ; Bernardo Pons-Estelm ; Roland Jonssono ; p ; Xianglan Lui ; Jacques-Eric Gottenbergq ; Juan-Manuel Anayar ; Deborah S. Cunninghame-Grahams ; Andrew J.W. Huangn ; Michael T. Brennant ; Pamela Hughesn ; Ilias Alevizosu ; Corinne Miceli-Richardv ; Edward C. Keystonew ; Vivian P. Bykerkx ; Gideon Hirschfieldy ; Gang Xiez ; Wan-Fai Ngaa ; Gunnel Nordmarkab ; Sara Magnusson Bucherac ; Per Erikssonae ; Roald Omdalad ; Nelson L. Rhodusaf ; Maureen Rischmuellerag ; ah ; Michael Rohrern ; Marie Wahren-Herleniusai ; Torsten Witteaj ; Xavier Mariettev ; Christopher J. Lessarda ; John B. Harleye ; f ; ak ; Kathy L. Sivilsa ; b ; R. Hal Scofielda ; b ; c ; d ; hal-scofield@omrf.ouhsc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sjö ; gren's syndrome ; X chromosome ; Klinefelter's syndrome ; Sex bias
- 刊名：Clinical Immunology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：168
- 期：Complete
- 页码：25-29
- 全文大小：315 K
文摘
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Sjögren’s syndrome has a strong sex bias
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Four of 126 Sjögren’s men had 47,XXY
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This result is statistically higher than that found in controls or men with RA but not different from that found among men with SLE
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An X chromosome dose effect may mediate sex bias in Sjögren’s syndrome.