A novel Bodipy-based fluorescent probe for Au³⁺ ions with high selectivity and its application to bioimaging

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• 作者：Yue WangAuthor Vitae ; Yawei LiuAuthor Vitae ; Junfeng Miao ; Minghao Ren ; Wei GuoAuthor Vitae ; Xin Lv ; ^{lvxin@sxu.edu.cn" class="auth_mail" title="E-mail the corresponding author}Author Vitae
• 关键词：Fluorescent probes ; Bodipy fluorophore ; Gold ions
• 刊名：Sensors & Actuators: B. Chemical
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：226
• 期：Complete
• 页码：364-369
• 全文大小：1359 K

文摘

A novel fluorescent probe based on a boron dipyrromethene (Bodipy) derivative for Au³⁺ has been designed, synthesized, and characterized. The probe comprises a spectroscopic unit of Bodipy and a specific Au³⁺ binding unit of 2-(phenylethynyl)aniline. The probe itself is almost no fluorescence because of photo-induced intramolecular electron transfer from the aniline unit to the Bodipy moiety, whereas transforming the 2-(phenylethynyl)aniline unit into the 2-phenylindole by Au³⁺ induced intramolecular cyclization reaction gives rise to strong fluorescence emission. In the system, an excellent selectivity toward the detection of Au³⁺ in aqueous solution over a wide range of tested cations was observed. Moreover, this probe can be used to detect Au³⁺ in real water samples, and can be used for fluorescent bioimaging of Au³⁺ in living cells.