Comparison of the long-term behavioral effects of neonatal exposure to retigabine or phenobarbital in rats
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- 作者：Sari Frankel ; Natalia Medvedeva ; Samuel Gutherz ; Catherine Kulick ; Alexei Kondratyev1 ; Patrick A. Forcelli ; paf22@georgetown.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anticonvulsant ; Development ; Neonatal ; Epilepsy ; Antiepileptic drug
- 刊名：Epilepsy & Behavior
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：57
- 期：part_PA
- 页码：34-40
- 全文大小：792 K
文摘
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Neonatal phenobarbital exposure increased anxiety-like behavior in adult rats.
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Neonatal retigabine exposure increased anxiety-like behavior in adult rats.
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Neonatal phenobarbital, but not retigabine, exposure impaired adult learning/memory.
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Neonatal phenobarbital decreases and retigabine increases adult social behavior.