Bis(3,5-dimethylpyrazol-1-yl)alkanones and their reactivity with [PdCl₂(NCMe)₂]: Isolation of bis(3,5-dimethylpyrazol-1-yl)propan-1-one palladium(II) chloride and C–H activation of propanone linker

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• 作者：Nangamso Miti ; Ilia A. Guzei ; Simphiwe M. Nelana ; James Darkwa
• 关键词：Bis(3 ; 5-dimethylpyrazolyl)alkanone ; Palladium(II) chloride complexes ; C– ; H activation ; Crystal structures
• 刊名：Inorganic Chemistry Communications
• 出版年：2010
• 出版时间：January 2010
• 年：2010
• 卷：13
• 期：1
• 页码：123-126
• 全文大小：343 K

文摘

Four new bis(3,5-dimethylpyrazol-1-yl)alkanones were prepared by the reaction of the respective alkanoyl chloride with 3,5-dimethylpyrazole: L1 from chloropropionyl chloride, L2 from 4-chlorobutyryl chloride, L3 from oxalyl chloride and L4 from adipoyl dichloride; all in moderate yields. Of the four compounds only L1 successfully reacts with [PdCl₂(NCMe)₂] to yield [PdCl₂(L1)] in 41 % yield, which on heating in toluene leads to C–H activation to produce [PdCl(L1′)], where L1′ is deprotonated L1, in very low yield.