Inhibition of BCL-2 leads to increased apoptosis and delayed neuronal differentiation in human ReNcell VM cells in vitro
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- 作者：Michael Frö ; hlicha ; 1 ; Alexandra Jaegera ; 1 ; Dieter G. Weissa ; Ralf Kriehubera ; b ; r.kriehuber@fz-juelich.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Apoptosis ; BCL-2 ; HA14-1 ; Human neural progenitor cells ; Neuronal differentiation
- 刊名：International Journal of Developmental Neuroscience
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：48
- 期：Complete
- 页码：9-17
- 全文大小：2863 K
文摘
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Inhibition of BCL-2 induces increased apoptosis of neural progenitor cells.
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Inhibition of BCL-2 causes a delayed neuronal cell differentiation.
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BCL-2 has a critical role in development of human neural progenitor cells.