Modelling confounding effects from extracerebral contamination and systemic factors on functional near-infrared spectroscopy

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• 作者：Matthew Caldwell^a ; Felix Scholkmann^b ; Ursula Wolf^c ; Martin Wolf^b ; Clare Elwell^a ; Ilias Tachtsidis^a ; ^{i.tachtsidis@ucl.ac.uk}
• 关键词：Functional near-infrared spectroscopy ; Brain ; Modelling ; Confounding ; Scalp ; CO2 reactivity
• 刊名：NeuroImage
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：143
• 期：Complete
• 页码：91-105
• 全文大小：1681 K
• 卷排序：143

文摘

Confounding of fNIRS haemoglobin signals is simulated using a computational model. Model is extended to simulate scalp haemodynamics. Changes in blood pressure and CO2 can mimic and mask functional activation. Experimental recording of systemic factors is recommended to aid interpretation.